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Journal : JURNAL ILMIAH KOHESI

PENGARUH PEMBERIAN MADU TERHADAP KADAR ALBUMIN PLASMA TIKUS PUTIH (Rattus norvegicus L.) JANTAN GALUR WISTAR YANG DI INDUKSI TUAK MUHAMMAD EGGA ACHYAR RAHMAN; ROBITAH ASFUR; FANI ADE IRMA; EMNI PURWONINGSIH
JURNAL ILMIAH KOHESI Vol 3 No 3 (2019): JURNAL ILMIAH KOHESI
Publisher : LP2MTBM MAKARIOZ

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Abstract

Tuak is the result of fermentation of leads taken from aren (Arenga pinnata) containing 88% water, 11.8% carbohydrate, 0.23% protein, 0.02% fat, 0.03% minerals and 5% alcohol. Alcohol metabolism in liver cells leads to an increase in free radicals resulting in oxidative stress that damages tissues in the liver. Objective: This study aims to determine the effect of giving honey on white rats (Rattus norvegicus L.) male wistar-induced strain of tuak. Method: True experiment design "prettest-posttest with control group design". Results: Significant results of plasma albumin levels between control and treatment groups were p> 0.05. Conclusion: Provision of honey 1.35 mL /rat/ day for 15 days had an effect on the increase of plasma albumin level which previously decrease due tuak 2.5 mL /rat/ day for 15 days.
EFEK PEMBERIAN REBUSAN KULIT MARKISA UNGU (PASSIFLORA EDULIS) SEBAGAI ANTIDIABETIK TERHADAP GAMBARAN HISTOPATOLOGI PANKREAS TIKUS YANG DIINDUKSI STREPTOZOTOSIN USWATUL KHOIROT; EMNI PURWONINGSIH; HUMAIRAH MEDINA LIZA LUBIS; LITA SEPTINA
JURNAL ILMIAH KOHESI Vol 5 No 1 (2021): JURNAL ILMIAH KOHESI
Publisher : LP2MTBM MAKARIOZ

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Abstract

DM is one of the greatest health problems around the world. Nowdays, we found many studies proved many plants whichcontain antioxidant have a potential as antidiabetic. Antioxidants are able to repair oxidative stress in pancreatic beta cellsthat overcome pancreatic tissues damage. One of the plant that contains rich antioxidant is purple passion fruit ( Passifloraeduils). This study used True Experimental method, with Post –Test Only Control Group Design, which only gave anobservation to a control group after being given a treatment. The sample of this study was white Wister strain male rats(Rattus Norvegisus L). The statistic study of this research used Kruskal Wallis and Mann-Whitney with a significance level ofp > 0,05, because the data were not normally distributed. Pancreatic histopathology improvement in the first treatment groupshowed a non-significant difference compared with positive controlled group (p< 0, 05). Pancreatic histopathologyimprovement in the second treatment group showed a significant different compared with positive controlled group(p< 0, 05). There was an effect of giving purple passion fruit skin decoction (Passiflora eduils) as anti-diabetic to the ratpancreas histopathology that inducted by streptozotosin.